Publications
Selected chemotherapy and seasonally transmitted Schistosoma haematobium infections in the middle valley of the Senegal River Basin.
De Clercq D, Hanne C, Vercruysse J.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2000, 94(2):198-9 (PMID : 10897368)
Predictive ultrasonographic criteria for portal hypertension due to Schistosoma mansoni in a recently established endemiz zone
Bonnard P, Lanuit R, Dompnier JP, Remoue F, Diop A, Ly A, Capron A, Riveau G.
Médecine tropicale: revue du corps de santé coloniale, 2000, 60(1):42-6 (PMID : 10989786)
The first cases of Schistosoma mansoni infection were reported in the Senegal River Basin ten years ago. Today endemicity is so high that prevalence rates exceed 90 p. 100 in some areas. Schistosomiasis sometimes goes undiagnosed until the occurrence of portal hypertension with rupture of esophageal varices. Endoscopy is the gold standard for detection of esophageal varices but it is impractical in remote areas. Ultrasonography has been proposed as a non-invasive alternative. The purpose of this study is to describe the results of simultaneous endoscopic and ultrasonographic assessment in 101 subjects from the Richard-Toll area of the Senegal River Basin. Findings showed that severe forms of schistosomiasis complicated by portal hypertension were already present in the region less 10 years after description of the first case. This study also proposes a diagnostic score for portal hypertension based on ultrasonographic findings. The features included in this score are thickening of portal vessel walls, portal vessel diameter, and collapsed appearance of the splenic vein during inspiration. In our hands this score allowed reliable prediction of the development of esophageal varices. Ultrasonography is a good tool for identifying severe forms of schistosomiasis. It should be useful for routine screening in recently established endemic zones.
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